General Research
Model: human
Electrolyzed hydrogen-rich water for oxidative stress suppression and improvement of insulin resistance: a multicenter prospective double-blind randomized control trial
Simplified Version Available
Hydrogen-Rich Water: A Simple Solution for Improving Insulin Resistance
A recent study found that drinking hydrogen-rich water improved insulin resistance and reduced oxidative stress in participants. This is significant because insulin resistance is a major risk factor for developing type 2 diabetes. By improving insulin resistance, we may be able to reduce the risk of developing type 2 diabetes and improve overall health.
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Publish Year 2021 Country Japan Rank Positive Journal Diabetology International Primary Topic Whole Body Secondary TopicDiabetes (Type II) Model Human Tertiary TopicGlucose Metabolism Vehicle Water (Electrolysis) pH Neutral Application Ingestion Comparison Complement
Methods
Results: There were no significant differences in the changes in HOMA-IR between the EHW and FW groups. However, lactate levels decreased significantly in the EHW group, and this decrease was significantly correlated with a reduction in HOMA-IR, fasting plasma glucose, and fasting plasma insulin level. Serum lactate level also significantly correlated to decreased insulin bolus secretion after 90 min with glucose loading in the EHW subjects with HOMA-IR > 1.73. No EHW treatment-related adverse effects were observed.
Results
Conclusion: There were no significant effect of EHW in the change in HOMA-IR in this study; larger-scale and longer-term study are needed to verify the effects of EHW in T2DM patients. Supplementary information: The online version contains supplementary material available at 10.1007/s13340-021-00524-3.