General Research Model: human

Evaluation of the safety and potential lipid-lowering effects of oral hydrogen-rich coral calcium (HRCC) capsules in patients with metabolic syndrome: a prospective case series study

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Hydrogen-Rich Coral Calcium: A Natural Way to Lower Cholesterol?

A recent study found that hydrogen-rich coral calcium (HRCC) capsules may help lower cholesterol levels in patients with metabolic syndrome. HRCC is a natural supplement that releases hydrogen gas slowly, which has antioxidant properties. While more research is needed, the results are promising for those looking for a complementary approach to support their heart health.

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Abstract

Publish Year 2023 Country Taiwan Rank Positive Journal Frontiers in Nutrition Primary Topic Whole Body Secondary TopicMetabolic Syndrome Model Human Tertiary TopicLipid Metabolism Vehicle Gas (Sustained Release) pH N/A Application Ingestion Comparison Complement

Background

Methods: The patients, all Taiwanese, were randomly assigned to 3 different doses (low, medium, and high) of HRCC capsules. The primary outcome was the adverse effects/symptoms during this 4-week use of HRCC capsules. The secondary outcome was lipid profile changes. Complete blood count, inflammatory biomarkers, and QOL were also measured before and after the course of HRCC.

Methods

Results: Sixteen patients with metabolic syndrome completed this study (7 males, 9 females; mean age: 62 years; range: 32-80). No obvious adverse effects were recorded. Only changes in blood TG reached significance. The baseline TG value was 193.19 μL (SD = 107.44), which decreased to 151.75 μL (SD = 45.27) after 4 weeks of HRCC (p = 0.04). QOL showed no significant changes.

Results

Conclusion: This study is the first human clinical trial evaluating HRCC capsules in patients with metabolic syndrome. Based on the safety and potential TG-lowering effects of short-term HRCC, further long-term investigations of HRCC are warranted. Clinical trial registration: [ClinicalTrials.gov], identifier [NCT05196295].