General Research
Model: human
Effectiveness and safety of hydrogen inhalation as an adjunct treatment in Chinese type 2 diabetes patients: A retrospective, observational, double-arm, real-life clinical study
Simplified Version Available
Breathing Easy: How Hydrogen Inhalation May Help Manage Type 2 Diabetes
A recent study found that hydrogen inhalation may be a useful adjunct treatment for type 2 diabetes, reducing oxidative stress and improving insulin sensitivity. This could be a new tool for people living with the condition, helping them better control their blood sugar levels and reduce their risk of complications. More research is needed, but the findings are promising.
Read Simplified ArticleAbstract
Publish Year 2023 Country China Rank Positive Journal Frontiers in Endocrinology Primary Topic Whole Body Secondary TopicDiabetes (Type II) Model Human Tertiary TopicOxidative Stress Vehicle Gas pH N/A Application Inhalation Comparison Complement
Methods
Results: In total, 1088 patients were selected into the analysis. Compared to the control group, subjects in HI group maintained greater improvement in the level of HbA1c (-0.94% vs -0.46%), FPG (-22.7 mg/dL vs -11.7 mg/dL), total cholesterol (-12.9 mg/dL vs -4.4 mg/dL), HOMA-IR (-0.76 vs -0.17) and HOMA-β (8.2% vs 1.98%) with all p< 0.001 post the treatment. Logistics regression revealed that the likelihood of reaching HbA1c< 7%, ≥ 7% to 1% reduction at the follow-up period was higher in the HI group, while patients in the control group were more likely to attain HbA1c ≥ 9%. Patients in HI group was observed a lower incidence of several AEs including hypoglycemia (2.0% vs 6.8%), vomiting (2.6% vs 7.4%), constipation (1.7% vs 4.4%) and giddiness (3.3% vs 6.3%) with significance in comparison to the control group.
Results
Conclusion: HI as an adjunct therapy ameliorates glycemic control, lipid metabolism, insulin resistance and AE incidence of T2DM patients after 6-month treatment, presenting a noteworthy inspiration to existing clinical diabetic treatment.