General Research Model: pig

The Effect of Hydrogen Inhalation on Temporary Threshold Shift Following Simultaneous Exposure to Noise and Carbon Monoxide in Guinea Pigs

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How Hydrogen Inhalation Can Protect Your Hearing from Noise and Pollution

A 2018 study found that hydrogen inhalation can help reduce temporary hearing loss caused by noise and carbon monoxide exposure in guinea pigs. This has implications for humans who work in noisy environments or are exposed to pollution. Hydrogen inhalation might be a simple way to protect our hearing and prevent permanent damage.

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Abstract

Publish Year 2018 Country Iran Rank Positive Journal Health Scope Primary Topic Ear Secondary TopicEnvironmental Pollution Model Guinea Pig Tertiary TopicCarbon Monoxide Poisoning Vehicle Gas pH N/A Application Inhalation Comparison Complement

Background

Methods: Twelve Guinea pigs were randomly divided into two different groups: (1) Exposed to noise plus carbon monoxide and (2) exposed to noise plus carbon monoxide along with the inhalation of hydrogen. Auditory brainstem responses (ABRs) at different frequencies of 2, 4, 8, and 16 kHz were measured before and immediately after the exposure.

Methods

Results: The ABR thresholds measured immediately after the simultaneous exposure to noise and carbon monoxide significantly increased at all frequencies in group 1 while in group 2, the ABR thresholds measured immediately after the inhalation of hydrogen significantly reduced at 4, 8, and 16 kHz (P values < 0.05). Conclusions: This finding indicates that there is a protective effect associated with the inhalation of 2% hydrogen on the development of hearing loss after the simultaneous exposure to noise and carbon monoxide and this effect was fairly significant at higher frequencies.