General Research
Model: mouse
Intermittent environmental exposure to hydrogen prevents skin photoaging through reduction of oxidative stress
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How Hydrogen Gas Can Help Prevent Skin Aging from Sun Damage
A recent study found that intermittent exposure to hydrogen gas can prevent skin aging caused by sun damage in mice. The gas reduced oxidative stress, which is like a fire that damages skin cells. While more research is needed, this could lead to a simple and non-invasive way to protect human skin from sun damage.
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Publish Year 2023 Country Japan Rank Positive Journal Geriatrics & Gerontology International Primary Topic Skin Secondary TopicAging Model Mouse Tertiary TopicUV Radiation Vehicle Gas pH N/A Application Inhalation Comparison Complement
Methods
Results: Intermittent administration of hydrogen gas by our system prevented UVA-induced epidermal signs, such as hyperplasia, melanogenesis and appearance of senescence cells, and UVA-induced dermal signs, such as collagen degradation. In addition, we detected attenuation of DNA damage in the hydrogen exposure group as indirect evidence that intermittent exposure to hydrogen gas reduced oxidative stress. Conclusions: Our findings support the notion that long-term, intermittent environmental exposure to hydrogen gas in daily life has a beneficial effect on UVA-induced photoaging. Geriatr Gerontol Int 2023; 23: 304-312.