Hydrogen Water
General Research Model: mouse

Hydrogen Water Drinking Exerts Antifatigue Effects in Chronic Forced Swimming Mice via Antioxidative and Anti-Inflammatory Activities

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Hydrogen Water: The Secret to Reducing Fatigue?

A study found that drinking hydrogen water can help reduce fatigue in mice by neutralizing free radicals and reducing muscle damage. Hydrogen water has antioxidant and anti-inflammatory properties, making it a potential natural remedy for fatigue. You can make hydrogen water at home using a water ionizer or hydrogen generator.

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Abstract

Publish Year 2018 Country South Korea Rank Positive Journal BioMed Research International Primary Topic Whole Body Secondary TopicExcercise Model Mouse Tertiary TopicFatigue Vehicle Water (Dissolved) pH Neutral Application Ingestion Comparison Complement

Results

Conclusion: This study shows antifatigue effects of HW drinking in chronic forced swimming mice via metabolic coordination and immune-redox balance. In that context, drinking HW could be applied to the alternative and safety fluid remedy for chronic fatigue control.

Purpose

Materials and methods: Twelve-week-old C57BL6 female mice were divided into nonstressed normal control (NC) group and stressed group: (purified water/PW-treated group and HW-treated group). Stressed groups were supplied with PW and HW, respectively, ad libitum and forced to swim for the stress induction every day for 4 consecutive weeks. Gross antifatigue effects of HW were assessed by swimming endurance capacity (once weekly for 4 wk), metabolic activities, and immune-redox activities. Metabolic activities such as blood glucose, lactate, glycogen, blood urea nitrogen (BUN), and lactate dehydrogenase (LDH) as well as immune-redox activities such as reactive oxygen species (ROS), nitric oxide (NO), glutathione peroxidase (GPx), catalase, and the related cytokines were evaluated to elucidate underlying mechanism. Blood glucose and lactate were measured at 0 wk (before swimming) and 4 wk (after swimming).