General Research
Model: human
Hydrogen-Rich Water Ameliorates Metabolic Disorder via Modifying Gut Microbiota in Impaired Fasting Glucose Patients: A Randomized Controlled Study
Simplified Version Available
Hydrogen-Rich Water: A Natural Solution for Metabolic Disorders
A recent study found that drinking hydrogen-rich water can help improve metabolic disorders by changing the balance of gut microbes. This natural solution could be a key to managing conditions like high blood sugar and heart disease. By taking care of our gut health, we may be able to prevent some diseases and feel healthier overall.
Read Simplified ArticleAbstract
Publish Year 2023 Country China Rank Positive Journal Antioxidants Primary Topic Intestine Secondary TopicMetabolic Syndrome Model Human Tertiary TopicGut Microbiome Vehicle Water (Electrolysis) pH Neutral Application Ingestion Comparison Complement
Methods
Results: Both pure water and HRW demonstrated a significant reduction in fasting blood glucose in IFG patients, with a significant difference between pure water and HRW after eight weeks. Among IFG patients with abnormal pre-experimental fatty liver, 62.5% (10/16) in the HRW group and 31.6% (6/19) in the pure water group achieved remission. Furthermore, 16S RNA analysis revealed HRW-modified gut microbiota dysbiosis in the fecal samples of IGF patients. Through Pearson correlation analysis, the differential gut microbiota obtained by 16S analysis was found to be highly correlated with nine metabolites.
Results
Conclusion: H2 slightly improved metabolic abnormalities and gut microbiota dysbiosis, providing a novel target and theoretical basis for the prevention and treatment of blood glucose regulation in patients with IFG.