General Research
Model: mouse
Hydrogen-rich saline protects immunocytes from radiation-induced apoptosis
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The Power of Hydrogen-Rich Saline: Protecting Cells from Radiation Damage
A 2012 study found that hydrogen-rich saline can protect cells from radiation damage, which could lead to new treatments for cancer patients undergoing radiation therapy. This discovery has implications for human health and wellbeing. Hydrogen-rich saline could be used to protect healthy cells during radiation therapy, making the treatment more effective and safer.
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Publish Year 2012 Country China Rank Positive Journal Medical Science Monitor Primary Topic Whole Body Secondary TopicCancer Model Mouse Tertiary TopicRadioprotection Vehicle Saline (Dissolved) pH Neutral Application Injection Comparison Complement
Background
Results: We demonstrated H2-rich medium pretreatment reduced •OH level in AHH-1 cells. We also showed H2 reduced radiation-induced apoptosis in thymocytes and splenocytes in living mice. Radiation-induced caspase 3 activation was also attenuated by H2 treatment. Finally, we found that H2 rescued the radiation-caused depletion of white blood cells (WBC) and platelets (PLT). Conclusions: This study suggests that H2 protected the immune system and alleviated the hematological injury induced by IR.