General Research Model: mouse

Hydrogen (H2) Inhibits Isoproterenol-Induced Cardiac Hypertrophy via Antioxidative Pathways

Simplified Version Available

How Hydrogen Gas Can Help Protect Your Heart

A 2016 study found that hydrogen gas may help protect the heart by reducing cardiac hypertrophy. The gas works by boosting antioxidative pathways, which help remove harmful substances from the body. This discovery could potentially lead to new treatments for heart conditions.

Read Simplified Article

Abstract

Publish Year 2016 Country China Rank Positive Journal Frontiers in Pharmacology Primary Topic Heart Secondary TopicHeart Attack Model Mouse Tertiary TopicDrug Toxicity (Isoproterenol) Vehicle Gas pH N/A Application Injection Comparison Complement

Background

Hydrogen (H2) has been shown to have a strong antioxidant effect on preventing oxidative stress-related diseases. The goal of the present study is to determine the pharmacodynamics of H2 in a model of isoproterenol (ISO)-induced cardiac hypertrophy. Methods: