General Research
Model: human
Feasibility and Safety of Hydrogen Gas Inhalation for Post-Cardiac Arrest Syndrome – First-in-Human Pilot Study
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Breathing New Life: Can Hydrogen Gas Help After Cardiac Arrest?
Researchers in Japan studied the use of hydrogen gas inhalation to help patients recover from post-cardiac arrest syndrome, finding it to be safe and potentially beneficial. This breakthrough could lead to new treatments for cardiac arrest recovery. The study offers hope for improved outcomes after cardiac arrest.
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Publish Year 2016 Country Japan Rank Positive Journal Circulation Journal Primary Topic Heart Secondary TopicCardiac Arrest Model Human Tertiary TopicHydrogen Safety Vehicle Gas pH N/A Application Inhalation Comparison Complement
Background
Results:Between January 2014 and January 2015, 21 of 107 patients with out-of-hospital cardiac arrest achieved spontaneous return of circulation. After excluding 16 patients with specific criteria, 5 patients underwent HI together with target temperature management (TTM). No undesirable effects attributable to HI were observed and 4 patients survived 90 days with a favorable neurological outcome. Conclusions: HI in combination with TTM is a feasible therapy for patients with PCAS.