General Research
Model: mouse
Effects of hydrogen water on paraquat-induced pulmonary fibrosis in mice
Simplified Version Available
Can Hydrogen Water Help Protect Lungs from Toxic Damage?
A 2015 study found that hydrogen water may help protect lungs from toxic damage caused by paraquat, a type of pesticide. The study showed that mice that drank hydrogen water had less lung damage and improved survival rates. This could have implications for humans who work with toxic substances or live in polluted areas.
Read Simplified ArticleAbstract
Publish Year 2015 Country Japan Rank Positive Journal Kitasato Medical Journal Primary Topic Lung Secondary TopicEnvironmental Pollution Model Mouse Tertiary TopicPesticide Toxicity (Paraquat) Vehicle Water, Commercial (Blue Mercury) pH Neutral Application Ingestion Comparison Complement
Methods
Results: Pneumodynamic analysis revealed that elastance (E) (P = 0.010) and hysteresivity (eta) (P = 0.048) were significantly lower in the PQ + HW group than that in the PQ group. Although no significant difference was observed in compliance, it tended to be higher in the PQ + HW group. Histologic findings showed that inflammatory cell infiltration and fibrosis were comparatively lower in the PQ + HW group.
Results
Conclusion: The results of the present study suggest that HW may prevent the development of PQinduced pulmonary injury.