General Research Model: rat

Effect of hydrogen-rich water on acute peritonitis of rat models

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Hydrogen-Rich Water: A Promising Solution for Reducing Inflammation

A 2014 study found that hydrogen-rich water reduced inflammation and improved symptoms of peritonitis in rat models. This exciting discovery suggests that hydrogen-rich water could be a useful tool in reducing inflammation and fighting off diseases. By incorporating hydrogen-rich water into daily life, people may be able to improve their overall health and reduce their risk of disease.

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Abstract

Publish Year 2014 Country China Rank Positive Journal International Immunopharmacology Primary Topic Peritonium Secondary TopicSepsis Model Rat Tertiary TopicPeritonitis Vehicle Water, Commercial (Izumio) pH Neutral Application Gavage Comparison Complement

Methods

Results: Three models showed the same result that hydrogen-rich water had an efficient protective effect on acute peritonitis. HRW could significantly lower the levels of WBCs, plasma endotoxin and cytokines, enhance GSH activity and reduce MPO and MDA activities in the peritoneum tissue when compared with that of groups with only saline treated. Simultaneously, we found that HRW could also decrease the NF-κB expression in the peritoneum tissues.

Results

Conclusion: Hydrogen-rich water could alleviate the severity of acute peritonitis, and it might perform this function by its anti-inflammation, anti-oxidation and anti-bacterial effects and reducing NF-κB expression in the peritoneum tissues.