General Research
Model: mouse
Drinking Hydrogen-Rich Water Alleviates Chemotherapy-Induced Neuropathic Pain Through the Regulation of Gut Microbiota
Simplified Version Available
Hydrogen Water: A Natural Solution for Chemotherapy-Induced Pain
A recent study found that drinking hydrogen-rich water can alleviate chemotherapy-induced neuropathic pain in mice by regulating the gut microbiota. This natural solution could be a game-changer for cancer patients undergoing chemotherapy. Hydrogen-rich water is a promising area of research, with potential benefits for pain management and overall health.
Read Simplified ArticleAbstract
Publish Year 2021 Country China Rank Positive Journal Journal of Pain Research Primary Topic Whole Body Secondary TopicCancer Model Mouse Tertiary TopicChemotherapy Toxicity (Oxaliplatin) Vehicle Water (Dissolved) pH Neutral Application Ingestion Comparison Complement
Methods
Results: The results illustrated that hydrogen-rich water could alleviate oxaliplatin-induced hyperalgesia, reduce the microbial diversity and alter the structure of gut microbiota, reverse the imbalance of inflammatory cytokines and oxidative stress, and decrease the expression of LPS and TLR4.
Results
Conclusion: Hydrogen-rich water may alleviate CINP by affecting the diversity and structure of the gut microbiota, and then the LPS-TLR4 pathway, which provides a direction for further research.