General Research
Model: human
Consumption of water containing over 3.5 mg of dissolved hydrogen could improve vascular endothelial function
Simplified Version Available
The Power of Hydrogen-Rich Water: Unlocking Better Heart Health
Drinking water with high levels of dissolved hydrogen can improve heart health by reducing oxidative stress and improving vascular endothelial function. This can help reduce the risk of heart disease, high blood pressure, and atherosclerosis. Hydrogen-rich water is a promising way to boost heart health, and more research is being done to explore its benefits.
Read Simplified ArticleAbstract
Publish Year 2014 Country Japan Rank Positive Journal Vascular Health and Risk Management Primary Topic Heart Secondary TopicAtherosclerosis Model Human Tertiary TopicOxidative Stress Vehicle Water (Electrolysis) pH Alkaline Application Ingestion Comparison Complement
Background
Methods: The efficacy of water containing a high concentration of H2 was tested by measuring flow-mediated dilation (FMD) of the brachial artery (BA). The subjects were randomly divided into two groups: the high-H2 group, who drank high-H2 water containing 7 ppm H2 (3.5 mg H2 in 500 mL water); and the placebo group. Endothelial function was evaluated by measuring the FMD of the BA. After measurement of diameter of the BA and FMD at baseline, volunteers drank the high-H2 water or placebo water immediately and with a 30-minute interval; FMD was compared to baseline.
Methods
Results: FMD increased in the high-H2 group (eight males; eight females) from 6.80%±1.96% to 7.64%±1.68% (mean ± standard deviation) and decreased from 8.07%±2.41% to 6.87%±2.94% in the placebo group (ten males; eight females). The ratio to the baseline in the changes of FMD showed significant improvement (P<0.05) in the high-H2 group compared to the placebo group.
Results
Conclusion: H2 may protect the vasculature from shear stress-derived detrimental ROS, such as the hydroxyl radical, by maintaining the nitric oxide-mediated vasomotor response.