General Research Model: human

Biological Effects of Electrolyzed Water in Hemodialysis

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Can Electrolyzed Water Revolutionize Kidney Treatment?

A Japanese study found that electrolyzed water can reduce inflammation in people undergoing hemodialysis, a treatment for kidney problems. The alkaline properties of the water help balance out acidity in the body, promoting healing. This breakthrough could lead to new and improved treatments for people with kidney problems.

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Abstract

Publish Year 2009 Country Japan Rank Positive Journal Nephron Clinical Practice Primary Topic Kidney Secondary TopicHaemodialysis Model Human Tertiary TopicInflammation Vehicle Water (Electrolysis) pH Alkaline Application Injection Comparison Complement

Background

Methods: Dialysis solution with H(2) (average of 48 ppb) was produced by mixing dialysate concentrates and reverse osmosis water containing dissolved H(2) generated by a water electrolysis technique. Subjects comprised 21 stable patients on standard HD who were switched to the test HD for 6 months at three sessions a week.

Methods

Results: During the study period, no adverse clinical signs or symptoms were observed. A significant decrease in systolic blood pressure (SBP) before and after dialysis was observed during the study, and a significant number of patients achieved SBP <140 mmHg after HD (baseline, 21%; 6 months, 62%; P < 0.05). Changes in dialysis parameters were minimal, while significant decreases in levels of plasma monocyte chemoattractant protein 1 (P < 0.01) and myeloperoxidase (P < 0.05) were identified. Conclusions: Adding H(2) to haemodialysis solutions ameliorated inflammatory reactions and improved BP control. This system could offer a novel therapeutic option for control of uraemia.