General Research
Model: in_vitro
Antifungal effect of electrolyzed hydrogen water on Candida albicans biofilm
Simplified Version Available
The Power of Hydrogen Water: Fighting Fungal Infections Naturally
A 2015 study found that electrolyzed hydrogen water has a strong antifungal effect against Candida albicans biofilms, making it a potential natural solution for preventing and treating fungal infections. This discovery could lead to new ways to combat mouth infections and other diseases. Hydrogen water's benefits extend beyond oral health, with research exploring its potential for treating lung diseases and chronic fatigue syndrome.
Read Simplified ArticleAbstract
Publish Year 2015 Country South Korea Rank Positive Journal Journal of Dental Rehabilitation and Applied Science Primary Topic Mouth Secondary TopicFungal Infection Model Cell Culture Tertiary TopicCandida Yeast Infection Vehicle Water (Electrolysis) pH Alkaline Application Irrigation Comparison Complement Palladium
Methods
Results: The electrolyzed water using palladium electrode (EWP) exhibited antifungal effect on blastoconidia of C. albicans. Also, the EWP significantly has antifungal activity against C. albicans biofilm and hyphae. In the electrolyzed water using various metal electrodes, only the EWP have antifungal activity.
Results
Conclusion: The EWP may use a gargle solution and a soaking solution for prevention of oral candidiasis and denture-related stomatitis due to antifungal activity.
Purpose
Methods: C. albicans was cultured by sabouraud dextrose broth and F-12 nutrient medium in aerobic and 5% CO2 condition to form blastoconidia (yeast) and hyphae type, respectively. For formation of C. albicans biofilm, C. albicans was cultivated on rough surface 6-well plate by using F-12 nutrient medium in CO2 incubator for 48 hr. After electrolyzing tap water using various metal electrodes, the blastoconidia and hyphal type of C. albicans were treated with electrolyzed water. C. albicans formed blastoconidia and hyphae type when they were cultured by sabouraud dextrose broth and F-12 nutrient medium, respectively.