General Research
Model: human
Assessment of the effects of hydrogen water on human gingival fibroblast cell culture in patients with chronic periodontitis
Simplified Version Available
How Hydrogen Water Can Help Fight Gum Disease
A 2023 study in India found that hydrogen water can help reduce inflammation and improve gum health in people with chronic periodontitis. This could lead to a new, simple way to manage gum disease. More research is needed, but the initial findings are promising. Hydrogen water might offer a new tool in the fight against gum disease, making it an interesting area of study for those looking for innovative health solutions.
Read Simplified ArticleAbstract
Publish Year 2023 Country India Rank Positive Journal Journal of Indian Society of Periodontology Primary Topic Mouth Secondary TopicPeriodontitis Model Cell Culture Tertiary TopicInflammation Vehicle Water (Electrolysis) pH Neutral Application Immersion Comparison Complement
Background
Materials and methods: The gingival tissue samples were obtained from 26 subjects (13 periodontally healthy individuals and 13 chronic periodontitis patients) and processed. The human gingival fibroblasts were cultured and the assays were commenced once adequate growth was detected. The effect of hydrogen water on cell viability was checked by neutral red assay, while the migration potential was assessed by transwell migration assay. The antioxidative potential of hydrogen water was evaluated by CUPRAC assay. Statistical analysis: Intergroup comparison was done using Mann-Whitney U-test. Intragroup comparison was done using Wilcoxon signed-rank test.
Results
Conclusion: Hydrogen water was nontoxic, increased the migratory capacity, and showed an antioxidative potential on human fibroblasts obtained from periodontally healthy individuals and patients with chronic periodontitis.