General Research
Model: mouse
Administration of Hydrogen-Rich Saline in Mice with Allogeneic Hematopoietic Stem-Cell Transplantation
Simplified Version Available
Hydrogen-Rich Saline: A Promising Treatment for Transplant Patients
Researchers in China studied the effects of hydrogen-rich saline on mice with allogeneic hematopoietic stem-cell transplantation, finding that it may reduce the severity of graft-versus-host disease. This could be a promising treatment for transplant patients, making the procedure safer and more effective. Further research is needed to confirm the findings and explore the potential benefits for humans.
Read Simplified ArticleAbstract
Publish Year 2015 Country China Rank Positive Journal Medical Science Monitor Primary Topic Bone Marrow Secondary TopicSurgery/Transplantation Model Mouse Tertiary TopicGraft-Versus-Host-Disease Vehicle Saline (Dissolved) pH Neutral Application Injection Comparison Complement
Background
Results: This study proves that hydrogen-rich saline increased the survival rate, reduced clinical and histopathological scores of aGVHD, promoted the recovery of white blood cells, reduced the serum cytokine levels, and reversed tissue damage after transplantation in mice. Conclusions: Hydrogen has potential as an effective and safe therapeutic agent in aGVHD.