General Research
Model: rat
Protective effect of hydrogen-rich saline on pressure overload-induced cardiac hypertrophyin rats: possible role of JAK-STAT signaling
Simplified Version Available
How Hydrogen Water May Help Protect Against High Blood Pressure
A study from China found that hydrogen-rich saline may help protect against cardiac hypertrophy, a condition where the heart muscle gets thicker due to high blood pressure. The study suggests that hydrogen water, which can be made at home, might help keep the JAK-STAT signaling pathway in balance, reducing the risk of cardiac hypertrophy. This is exciting news for those looking to protect their heart health.
Read Simplified ArticleAbstract
Publish Year 2018 Country China Rank Positive Journal BMC Cardiovascular Disorders Primary Topic Heart Secondary TopicHigh Blood Pressure Model Rat Tertiary TopicCardiac Hypertrophy Vehicle Saline (Dissolved) pH Neutral Application Injection Comparison Complement
Background
Results: The ratios of HW/BW and LVW/BW were shown in an order of Model > LHRS > HHRS > SHAM groups. The cardiac hypertrophy was also manifested with increased expressions of atrial natriuretic peptide (ANP), brain natriuretic peptides (BNP) and fibrosis of cardiac tissues in AAC-model group, which could likewise be restrained in LHRS and HHRS groups. Moreover, the JAK-STAT (Janus Kinase-Signal transducers and activators of transcription) signaling molecule expressions were decreased with HRS treatment. Conclusions: Our results showed a protective effect of HRS on pressure overload-induced cardiac hypertrophy in rats, which may be associated to a decreasing in JAK-STAT signaling pathway.