General Research Model: mouse

PPARα contributes to the therapeutic effect of hydrogen gas against sepsis-associated encephalopathy with the regulation to the CREB-BDNF signaling pathway and hippocampal neuron plasticity-related gene expression

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How Hydrogen Gas May Help Fight Brain Damage from Sepsis

Researchers in China found that hydrogen gas may help reduce brain damage caused by sepsis, a life-threatening condition that can lead to cognitive impairment and memory loss. The study showed that hydrogen gas activates a protein that promotes the growth of new neurons and protects existing ones from damage. This discovery may lead to new treatments for sepsis and improved outcomes for patients.

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Abstract

Publish Year 2022 Country China Rank Positive Journal Brain Research Bulletin Primary Topic Brain Secondary TopicSepsis Model Mouse Tertiary TopicCognitive Impairment Vehicle Gas pH N/A Application Inhalation Comparison Complement