General Research
Model: mouse
Molecular hydrogen protects against ischemia-reperfusion injury in a mouse fatty liver model via regulating HO-1 and Sirt1 expression
Simplified Version Available
Hydrogen Power: How a Simple Gas Can Protect Your Liver
A study in Japan found that molecular hydrogen can protect the liver from ischemia-reperfusion injury in mice with fatty livers. The hydrogen worked by increasing the expression of two important proteins, HO-1 and Sirt1, which help protect and repair liver cells. This discovery could lead to new treatments for liver diseases in humans.
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Publish Year 2018 Country Japan Rank Positive Journal Nature Scientific Reports Primary Topic Liver Secondary TopicFatty Liver Disease (Nonalcoholic) Model Mouse Tertiary TopicIschemia-Reperfusion Injury Vehicle Saline (Dissolved) pH Neutral Application Injection Comparison Complement