General Research
Model: rat
Inhaled Hydrogen Gas Therapy for Prevention of Renal Ischemia/Reperfusion Injury in Rat Model
Simplified Version Available
How Inhaling Hydrogen Gas May Protect Your Kidneys During Surgery
Inhaling hydrogen gas may protect your kidneys during surgery by reducing inflammation and oxidative stress. A study using a rat model found that hydrogen gas inhalation prevented kidney damage. This could be a simple and effective way to safeguard your kidneys during surgical procedures.
Read Simplified ArticleAbstract
Publish Year 2013 Country Turkey Rank Positive Journal Turkiye Klinikleri Journal of Medical Sciences Primary Topic Kidney Secondary TopicSurgery/Transplantation Model Rat Tertiary TopicIschemia-Reperfusion Injury Vehicle Gas pH N/A Application Inhalation Comparison Complement
Methods
Results: Kidneys from control rats (Group 2) exhibit significant injury characterized by marked histological changes characteristic of I/R injury in the outer medulla and cortex regions. Histological alterations were markedly reduced and all histological scores for renal injury were significantly lower in specimens from the hydrogen-I/R group compared to the control group (p=0.001).
Results
Conclusion: In this study, we demonstrated that hydrogen gas significantly attenuated renal I/R injury in early and late periods, and may have therapeutic potential against various clinical conditions involving I/R injury.