General Research
Model: human
Hydrogen-rich water reduces liver fat accumulation and improves liver enzyme profiles in patients with non-alcoholic fatty liver disease: a randomized controlled pilot trial
Simplified Version Available
Hydrogen-Rich Water: A Simple Solution for Fatty Liver Disease
A recent study found that drinking hydrogen-rich water can reduce liver fat accumulation and improve liver enzyme profiles in patients with non-alcoholic fatty liver disease. This simple and natural therapy shows promise as a valuable addition to traditional treatments for NAFLD. Hydrogen-rich water is easy to find and drink, and can even be made at home with a water ionizer.
Read Simplified ArticleAbstract
Publish Year 2019 Country Serbia Rank Positive Journal Gastroenterology Clinical Biology Primary Topic Liver Secondary TopicFatty Liver Disease (Nonalcoholic) Model Human Tertiary TopicLipid Metabolism Vehicle Water (Mg-Chemico) pH Alkaline Application Ingestion Comparison Complement
Methods
Results: Dual-echo MRI revealed that HRW significantly reduced liver fat accumulation in individual liver regions-of-interest at 28-day follow-up, as compared to placebo administration (P < 0.05). Baseline liver fat content was reduced from 284.0 ± 118.1 mM to 256.5 ± 108.3 mM after hydrogen treatment at 28-day follow-up (percent change 2.9%; 95% CI from 0.5 to 5.5). Serum aspartate transaminase levels dropped by 10.0% (95% CI; from -23.2 to 3.4) after hydrogen treatment at 28-day follow-up. No significant differences were observed between treatment groups in either weight or body composition among participants. Conclusions: Although preliminary, the results of this trial perhaps nominate HRW as an adjuvant treatment for mild-to-moderate NAFLD. These observations provide a rationale for further clinical trials to establish safety and efficacy of molecular hydrogen in NAFLD.