General Research Model: mouse

Hydrogen gas inhibits high mobility group box 1 release in septic mice by up-regulation of heme oxygenase-1

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How Hydrogen Gas Fights Sepsis: A Breakthrough for Lung Health

A 2015 study found that hydrogen gas inhalation reduced lung injury and improved survival rates in mice with sepsis. Hydrogen gas works by boosting a protective protein called heme oxygenase-1, which reduces inflammation and oxidative stress. This breakthrough could lead to new treatments for sepsis and lung injury in humans.

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Abstract

Publish Year 2015 Country China Rank Positive Journal Journal of Surgical Research Primary Topic Lung Secondary TopicSepsis Model Mouse Tertiary TopicLung Injury Vehicle Gas pH N/A Application Inhalation Comparison Complement