General Research Model: mouse

Hydrogen gas alleviates sepsis-induced neuroinflammation and cognitive impairment through regulation of DNMT1 and DNMT3a-mediated BDNF promoter IV methylation in mice

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How Hydrogen Gas May Help Reduce Brain Inflammation and Improve Cognitive Function

A study in mice found that hydrogen gas inhalation reduced brain inflammation and improved cognitive function in cases of sepsis. This was achieved by regulating the methylation of the BDNF gene, which is crucial for brain health. The findings suggest potential applications for hydrogen gas therapy in treating brain inflammation and cognitive impairment.

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Abstract

Publish Year 2021 Country China Rank Positive Journal International Immunopharmacology Primary Topic Brain Secondary TopicSepsis Model Mouse Tertiary TopicEncephalopathy Vehicle Gas pH N/A Application Inhalation Comparison Complement