General Research Model: rat

Hydrogen enriched saline alleviates morphine tolerance via inhibiting neuroinflammation, GLT-1, GS nitration and NMDA receptor trafficking and functioning in the spinal cord of rats

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How Hydrogen-Enriched Saline May Help Reduce Morphine Tolerance

A recent study found that hydrogen-enriched saline can help alleviate morphine tolerance in rats by reducing neuroinflammation and inhibiting certain chemical reactions. This could lead to more effective pain management and reduced risk of addiction for people who rely on morphine. Hydrogen therapy has shown promise in other areas, including reducing fatigue and protecting the liver.

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Abstract

Publish Year 2021 Country China Rank Positive Journal Neuroscience Letters Primary Topic Brain Secondary TopicAddiction Model Rat Tertiary TopicDrug Toxicity (Morphine) Vehicle Saline (Dissolved) pH Neutral Application Injection Comparison Complement