General Research Model: human

Electrolyzed Saline Irrigation for Elimination of Bacterial Colonization in the Empyema Space

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Cleaning Out Infections with a Simple Solution

A Japanese study found that electrolyzed saline irrigation can help eliminate bacterial colonization in the empyema space, offering a promising new treatment option for lung infections. This simple solution uses an acidic environment to kill bacteria and reduce the risk of further infection. The study's findings could lead to better treatment options for people with lung infections, making it easier to breathe and recover.

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Abstract

Publish Year 2016 Country Japan Rank Positive Journal Surgical Infections Primary Topic Lung Secondary TopicSurgery/Transplantation Model Human Tertiary TopicBacterial Infection Vehicle Water (Electrolysis) pH Acidic Application Irrigation Comparison Complement

Background

Results: Sixteen patients were male and four were female, with a mean age of 66.5 ± 9.5 y (27-90 y). Bacterial cultures of the purulent effusions from all 20 patients had positive results. Seventeen patients subsequently underwent continuous catheter irrigation and drainage. No patient had chest pain during ES irrigation. Fever duration after mini VATS was 2.8 ± 1.8 d (0-5 d). Catheter indwelling time was 10.3 ± 7.2 d (3-33 d). Inflammatory markers significantly improved (p < 0.05) within a week after mini VATS. Eighteen patients achieved pleural disinfection, and two patients had residual pathogens, one of whom later died of lung abscess. Space closure was successful in 14 patients. No patient underwent subsequent open drainage. Nineteen (95%) patients were discharged from the hospital. This treatment was successful in 18 (90%) patients, and one (5.6%) patient experienced recurrence. Conclusions: The ES irrigation facilitates the rapid disinfection and closure of the empyema space.