General Research Model: human

Effects of alkaline water intake on gastritis and miRNA expression (miR-7, miR-155, miR-135b and miR-29c)

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The Power of Alkaline Water: Can it Soothe Gastritis and Reduce Cancer Risk?

A 2020 study found that drinking alkaline water can reduce inflammation and improve symptoms in patients with gastritis, while also affecting the expression of certain miRNAs linked to cancer development. Alkaline water may help lower the risk of stomach cancer and have a positive impact on miRNA expression. Staying hydrated with alkaline water may be a simple and effective way to support stomach health and potentially reduce cancer risk.

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Abstract

Publish Year 2020 Country Brazil Rank Positive Journal American Journal of Translational Research Primary Topic Stomach Secondary TopicCancer Model Human Tertiary TopicGastritis Vehicle Water (Electrolysis) pH Alkaline Application Ingestion Comparison Acidic Water Complement

Methods

Results: Endoscopic findings of gastritis were such different (less severe disease), P = 0.024; in 43% diagnosed with moderate gastritis upfront esophagogastroduodenoscopy (EGD) presented mild gastritis after the consumption of alkaline water, according to study methods; there were no worsening gastritis and there were a significant increase in the expression of miR-135b (P = 0.039) and miR-29c (P = 0.039).

Results

Conclusion: Modified pH range water (from 8.0 to 10.0) ingested for 5 months was able lead to a less severe gastritis according to the Sidney classification system, suggesting that this lifestyle change represented a clinical benefit in patients with gastritis on the Amazon region. In addition, higher expression of miR-135b and miR-29c was observed after the consumption of alkaline water for 5 months.