General Research
Model: rat
Effect of hydrogen inhalation on p38 MAPK activation in rats with lipopolysaccharide- induced acute lung injury
Simplified Version Available
Breathe Easy: How Hydrogen Inhalation Can Help With Lung Injury
A study found that hydrogen inhalation can help reduce lung injury in rats by reducing inflammation. This could have implications for human treatment and highlights the potential benefits of hydrogen therapy. You can even make hydrogen water at home using a water ionizer or hydrogen generator.
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Publish Year 2012 Country China Rank Positive Journal Journal of Southern Medical University Primary Topic Lung Secondary TopicSepsis Model Rat Tertiary TopicLung Injury Vehicle Gas pH N/A Application Inhalation Comparison Complement
Methods
Results: Hydrogen inhalation decreased the expression of p-p38 MAPK in the lung tissue, and significantly reduced TNF-α content in the lung tissue and serum of rats with ALI.
Results
Conclusion: Hydrogen inhalation can decrease the expression of TNF-α in the lung tissue and serum, and this effect may be related with reduced p38 MAPK expression and inhibition of p38 MAPK activation.