General Research
Model: mouse
Combination of Korean Red Ginseng Extract and Hydrogen-Rich Water Improves Spermatogenesis and Sperm Motility in Male Mice
Simplified Version Available
Boosting Male Fertility: How Korean Red Ginseng and Hydrogen-Rich Water Can Help
A study found that combining Korean Red Ginseng extract and hydrogen-rich water improved spermatogenesis and sperm motility in male mice. This natural combination may offer a new approach to improving male fertility. More research is needed to confirm these findings in humans, but the results are promising.
Read Simplified ArticleAbstract
Publish Year 2020 Country South Korea Rank Positive Journal Chinese Journal of Integrative Medicine Primary Topic Testes Secondary TopicInfertility Model Mouse Tertiary TopicSpermatogenesis Vehicle Water (Dissolved) pH Neutral Application Gavage Comparison Complement Ginseng
Methods
Results: HRW and KRG treatment stimulated spermatogenesis followed by increasing sperm production and sperm motility (P <0.05). These effects were strengthened synergistically by a HRGW mixture (P <0.05 or P <0.01). HRGW greatly increased the expressions of antioxidation, antiaging, spermatogenesis related genes and VEGF especially in aged mice (P <0.05). Serum testosterone and FSH levels also increased, while serum ROS level decreased (all P <0.05).
Results
Conclusion: HRGW increases sperm production and motility by enhancing antioxidation and stimulating spermatogenesis and sex hormone production, particularly in aged mice.