General Research
Model: rat
Alleviating effects of hydrogen on hyperhomocysteinemia and fatty liver induced by high-methionine diet
Simplified Version Available
Hydrogen Water: A Natural Solution for Liver Health
A recent study found that hydrogen water can help alleviate the effects of a high-methionine diet on the liver. The study showed that drinking hydrogen water reduced the levels of homocysteine in the blood and improved liver function. This is exciting news, as it suggests that hydrogen water may be a natural way to support liver health.
Read Simplified ArticleAbstract
Publish Year 2023 Country China Rank Positive Journal Chinese Journal of Applied Physiology Primary Topic Liver Secondary TopicLiver Disease Model Rat Tertiary TopicFatty Liver Disease (Nonalcoholic) Vehicle Water (Electrolysis) pH Neutral Application Ingestion Comparison Complement
Methods
Results: Compared with the CHOW group rats, the Hcy level in the blood of HMD rats was significantly increased significantly (P＜0.05). Pathological tissue sections showed liver enlargement, injury, and fatty liver in the rats; Compared with the HMD group rats, the HMD+HRW group rats showed a significant decrease in Hcy in the blood, reduced liver damage, and increased Hcy metabolism key enzyme activity and mRNA expression in the liver, with statistical differences (P＜0.05).
Results
Conclusion: Hydrogen has a significant improvement effect on liver injury induced by HMD diet in HHcy rats, possibly by enhancing the three metabolic pathways of Hcy to reduce excessive Hcy in the body, thereby improving liver metabolic function and symptoms of non-alcoholic fatty liver disease.