General Research
Model: rat
A novel fluid resuscitation protocol: Provide more protection on acute kidney injury during septic shock in rats
Simplified Version Available
New Hope for Kidney Protection: How a Simple Gas Could Save Lives
A recent study found that hydrogen gas can help protect kidneys from damage caused by septic shock. This simple treatment could save countless lives and has implications for various health conditions. By reducing inflammation and oxidative stress, hydrogen gas shows promise as a versatile therapeutic agent.
Read Simplified ArticleAbstract
Publish Year 2014 Country China Rank Positive Journal International Journal of Clinical and Experimental Medicine Primary Topic Kidney Secondary TopicSepsis Model Rat Tertiary TopicInflammation Vehicle Gas pH N/A Application Inhalation Comparison Complement
Methods
Results: Fluid resuscitation with 2% hydrogen inhalation decreased serum creatinine, blood urea nitrogen, and neutrophil gelatinase-associated lipocalin. It also reduced oxidative stress injury and decreased renal tumor necrosis factor-α and interleukin-6 levels compared with fluid resuscitation alone.
Results
Conclusion: Early fluid resuscitation plus 2% hydrogen inhalation provided more protection against AKI during septic shock.